a16z Podcast Network

The a16z podcast network features expert discussions on tech innovation across AI, health, finance, and culture, offering valuable insights from industry leaders, founders, and a16z partners for builders and the tech-curious alike.

Featured Episodes

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In the Vault
In the Vault: Finding a Single Source of AI Truth With Marty Chavez From Sixth Street
David Haber
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a16z Podcast
Systems Leadership for Disruptors and Incumbents
Robert Siegel, Jeffrey Immelt, Jeff Jordan, and Sonal Chokshi
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Bio Eats World
Discovery, Translation, and the State of Bio Today
Jorge Conde
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Bio Eats World
Evolving Embodied Intelligence
Li Fei-Fei, Surya Ganguli, Vijay Pande, and Lauren Richardson
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My First 16
My First 16: Competing in a Crowd of Incumbents with Mercury’s Immad Akhund
Seema Amble
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a16z Podcast
All About NFTs
Jesse Walden, Linda Xie, and Sonal Chokshi
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Bio Eats World
The Machine that Made the Vaccine
Stephane Bancel, Jorge Conde, and Hanne Winarsky
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a16z Podcast
Amazon Narratives — Memos, Working Backwards from Release, More
Colin Bryar, Bill Carr, and Sonal Chokshi
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Bio Eats World
Engineering an Epigenome Editor
Jonathan Weissman, Vijay Pande, and Lauren Richardson
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a16z Podcast
Crypto, an Oral Essay
Dan Boneh, Chris Dixon, Scott Kupor, Eddy Lazzarin, Alex Pruden, Arianna Simpson, Jesse Walden, Linda Xie, Ali Yahya, Sonal Chokshi, and Zoran Basich
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a16z Podcast
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Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

  • Steph Smith
  • Chris Dixon
  • David George
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The Critical Technology in Finding Critical Materials

  • Mfikeyi Makayi
  • George Gilchrist
  • Tom Hunt
  • Connie Chan
  • Steph Smith
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DeepSeek: America’s Sputnik Moment for AI?

  • Steph Smith
  • Martin Casado
  • Steven Sinofsky
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Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter

  • Ben Horowitz
  • Dr. Clarence Jones
  • Megan Holston Alexander
  • Steph Smith
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How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril

  • David George
  • Brian Schimpf
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RIP to RPA: How AI Makes Operations Work

  • Kimberly Tan
  • Steph Smith
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Marc Andreessen: Can Tech Finally Fix Healthcare?

  • Marc Andreessen
  • Vijay Pande
  • Julie Yoo
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Building Substack: Reinventing Culture through Subscriptions

  • Chris Best
  • Andrew Chen
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Crypto Trends for 2025: Stablecoins, App Stores, UX, and More

  • Sam Broner
  • Joachim Neu
  • Daren Matsuoka
  • Steph Smith
  • Sonal Chokshi
  • Robert Hackett
  • Maggie Hsu
  • Chris Lyons
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Super Staffing Healthcare, Codifying Compliance, & Scaling Services

  • Steph Smith
  • Julie Yoo
  • Angela Strange
  • Joe Schmidt
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Raising Health

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Raising Health
Raising Health

Voice AI: Solving Healthcare's Workforce Challenges with Ankit Jain

  • Ankit Jain
  • Julie Yoo
  • Olivia Webb
  • Kris Tatiossian
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Transforming Clinical Trials with Alexander Saint-Amand

  • Alexander Saint-Amand
  • Julie Yoo
  • Kris Tatiossian
  • Olivia Webb
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Scaling Medicaid Innovation with Afia Asamoah, Rajaie Batniji, and Sanjay Basu

  • Rajaie Batniji
  • Afia Asamoah
  • Sanjay Basu
  • Olivia Webb
  • Kris Tatiossian
  • Vineeta Agarwala
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Super Staffing in Healthcare with Munjal Shah

  • Munjal Shah
  • Kris Tatiossian
  • Julie Yoo
  • Olivia Webb
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Lessons from Healthcare Infrastructure Pioneers with Jeff Margolis

  • Jeff Margolis
  • Kris Tatiossian
  • Julie Yoo
  • Olivia Webb
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Rare Disease, Big Impact with Matt Wilsey

  • Matt Wilsey
  • Jorge Conde
  • Olivia Webb
  • Kris Tatiossian
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Bioorthogonal Chemistry with Carolyn Bertozzi

  • Jorge Conde
  • Olivia Webb
  • Carolyn Bertozzi
  • Kris Tatiossian
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Mastering Data with Sajith Wickramasekara

  • Sajith Wickramasekara
  • Jorge Conde
  • Kris Tatiossian
  • Jay Rughani
  • Olivia Webb
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Build Your Own Provider Network with Dan Rosenthal

  • Julie Yoo
  • Kris Tatiossian
  • Dan Rosenthal
  • Olivia Webb
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The Freedom to Choose Your Own Insurance with Chris Ellis and Adam Stevenson

  • Chris Ellis
  • Adam Stevenson
  • Julie Yoo
  • Kris Tatiossian
  • Jay Rughani
  • Olivia Webb
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AI + a16z

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AI + a16z
AI + a16z

Agents, Lawyers, and LLMs

  • Aatish Nayak
  • Kimberly Tan
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Reasoning Models Are Remaking Professional Services

  • Alex Immerman
  • George Sivulka
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Data Management for Enterprise LLMs

  • George Fraser
  • Guido Appenzeller
  • Derrick Harris
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From NLP to LLMs: The Quest for a Reliable Chatbot

  • Alan Nichol
  • Martin Casado
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Best of the Year: Building AI Companies

  • Andreas Blattman
  • Ben Firshman
  • Dean De Beer
  • Feross Aboukhadijeh
  • Jesse Zhang
  • Mohammad Norouzi
  • Naveen Rao
  • Nikhil Buduma
  • Patrick Esser
  • Robert Nishihara
  • Robin Rombach
  • Tony Holdstock-Brown
  • Derrick Harris
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Can AI Agents Finally Fix Customer Support?

  • Jesse Zhang
  • Kimberly Tan
  • Derrick Harris
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Building Developers Tools, From Docker to Diffusion Models

  • Ben Firshman
  • Matt Bornstein
  • Derrick Harris
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The Best Way to Achieve AGI Is to Invent It

  • Pedro Domingos
  • Martin Casado
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Neural Nets and Nobel Prizes: AI's 40-Year Journey from the Lab to Ubiquity

  • Anjney Midha
  • Derrick Harris
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How GPU Access Helps Startups Be Agile

  • Anjney Midha
  • Derrick Harris
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In the Vault

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In the Vault
In the Vault

Turning Developers Into Clients With Marco Argenti From Goldman Sachs

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Finding a Single Source of AI Truth With Marty Chavez From Sixth Street

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Placing Multiple Bets on a ‘Mosaic of Solutions’ With Former Global Payments CEO Jeff Sloan

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a16z Live

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a16z Live
a16z Live

How AI Is Changing Warfare, with Anduril CEO Brian Schimpf

  • David George
  • Brian Schimpf
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In The Vault: How AI is Powering Payments with Greg Ulrich

  • Greg Ulrich
  • Marc Andrusko
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How Jack Henry is Modernizing Banking Infrastructure

  • Ben Metz
  • Angela Strange
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Building a $20B+ Open Source Business with MongoDB's Eliot Horowitz

  • Seema Amble
  • Eliot Horowitz
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How Zapier Became Profitable in 3 years and Scaled to $5B with Wade Foster

  • Seema Amble
  • Wade Foster
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How Gusto Used Customer Input to Scale Growth with Tomer London

  • Seema Amble
  • Tomer London
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How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD

  • a16z
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a16z Growth's David George on His Frameworks for Late-Stage Investing

  • Tyler Hogge
  • Sterling Snow
  • David George
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Why Human Data is Key to AI: Alexandr Wang from Scale AI

  • Alexandr Wang
  • David George
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In the Vault: Assessing AI Impact vs. Hype with John Stecher of Blackstone

  • John Stretcher
  • David Haber
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16 minutes News

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16 minutes News
16 minutes News

Parasite, the Malaria (Tech & Science) Edition

  • Sonal Chokshi
  • Jorge Conde
  • Rajeev Venkayya
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Crypto at Congress: 'Watershed' Moment for Regulation and Web3

  • Tomicah TIllemann
  • Zoran Basich
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Inside the GameStop Drama; The U.S. Constitution, Auctioned

  • Marc Andreessen
  • Ken Griffin
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Steam Halts Web3 Games; FDA Approves Prostate Cancer AI

  • Jonathan Lai
  • Eddy Lazzarin
  • Eliezer Van Allen
  • Vineeta Agarwala
  • Jay Rughani
  • Zoran Basich
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mRNA for Flu Vaccine? AI Protein-Folding Goes Open Source

  • Jorge Conde
  • Zoran Basich
  • Vijay Pande
  • Vineeta Agarwala
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Opioid Crisis - How, Who, and Tech

  • Sonal Chokshi
  • Vijay Pande
  • Jorge Conde
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Ransomware Attacks on the Rise; Hackers Target IoT

  • Joel de la Garza
  • Zoran Basich
  • Martin Casado
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Science (and Tech), the Endless Frontier

  • Martin Casado
  • Sonal Chokshi
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Malaria Vaccine Breakthrough, Beyond the Buzz

  • Rajeev Venkayya
  • Jorge Conde
  • Sonal Chokshi
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Apple Event: Desktop-Tablet Convergence, Cord-Cutting, "Find Anything," & More

  • Zoran Basich
  • Steven Sinofsky
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Zone of Genius

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Zone of Genius
Zone of Genius

Evolve or Die: The Future of the Creative Process, Artist Authenticity, and the Value of the Music

  • Megan Holston-Alexander
  • Doug E. Fresh
  • Nicole Wyskoarko
  • Piff Marti
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More Than a Game: Why Are We Obsessed With Sports?

  • Megan Holston-Alexander
  • Que Gaskins
  • Robin Arzón
  • Nan Wang
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Comfort Food, Climate, and the Future of Our Plates

  • Megan Holston-Alexander
  • Julia Collins
  • Alvin Salehi
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My First 16

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My First 16
My First 16

Competing in a Crowd of Incumbents with Mercury's Immad Akhund

  • Seema Amble
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Doubling Down on Founder-Led Sales with Pilots Waseem Daher

  • Seema Amble
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Welding Yourself to Early Customers with Marqeta’s Jason Gardner

  • Seema Amble
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Creating a Supportive Builder Community with Plaid's Zach Perret

  • Seema Amble
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Launching a New Category with Modern Treasury's Dimitri Dadiomov

  • Seema Amble
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The Ben and Marc Show

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The Ben and Marc Show
The Ben and Marc Show

Las Vegas is Becoming the SAFEST City in America

  • Ben Horowitz
  • Marc Andreessen
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Trump is About to Change Everything For Tech Startups

  • Ben Horowitz
  • Marc Andreessen
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New AI Policy Update on Safety, Censorship & Unexpected Risks

  • Ben Horowitz
  • Marc Andreessen
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AI, Robotics & the New Global Arms Race

  • Ben Horowitz
  • Marc Andreessen
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Truth Terminal - The AI Bot That Became a Crypto Millionaire

  • Ben Horowitz
  • Marc Andreessen
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Trump Vs. Biden: Tech Policy

  • Ben Horowitz
  • Marc Andreessen
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Marc Andreessen on Building Netscape & the Birth of the Browser

  • Ben Horowitz
  • Marc Andreessen
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The Future of the American Dream

  • Ben Horowitz
  • Marc Andreessen
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AI, Robotics & the Future of Manufacturing

  • Ben Horowitz
  • Marc Andreessen
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Build Your Startup With AI

  • Ben Horowitz
  • Marc Andreessen
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