AI + a16z
The stakes are high. The opportunities are profound. From the creation of new medicines to ways to solve climate change, this is our vision for the AI-enabled future.
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Why AI Will Save the World
Marc AndreessenNo, AI won’t kill us all, take our jobs, or otherwise ruin society. The threat of not aggressively pursuing global AI dominance, however, is considerable. A counterpoint to the moral panic that is currently influencing AI policy.
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The Economic Case for Generative AI
Martin Casado and Sarah WangIt has typically been difficult for startups to reach escape velocity using AI as a core differentiator. But with generative AI, we’re already seeing use cases with orders-of-magnitude improvement in time, cost, and performance over previous AI waves.
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AI Revolutionaries


To date, a handful of large companies have captured the value created by advances in AI. With generative AI, that’s changing.
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In conversation with Martin Casado, a16z
The story behind the release of ChatGPT—and what it tells us about the future of AI and human-machine interactions.
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In conversation with Jonathan Lai, a16z
How is generative AI changing games and virtual world, as well as how we create them.
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In conversation with David George, a16z
Will AI take all the design jobs? The relationship between designers, developers, and AI…
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In conversation with Anjney Midha, a16z
Will scaling laws take us to AGI? Plus, how AI can be used to improve itself.
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In conversation with Bob Swan, a16z
Could AI copilots be the start of an industrial revolution for knowledge work?
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In conversation with Vijay Pande, a16z
An LLM for cells could revolutionize drug discovery, if we can bridge the divide between atoms and bits.
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In conversation with Ben Horowitz, a16z
Data wars inside and outside enterprises, and how they could impact the evolution of LLMs.
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In conversation with Sarah Wang, a16z
We’re at the dawn of universally accessible intelligence, but do we have the compute to power it?
Read the transcriptThe Builders: a16z's AI portfolio
- AKASA
- Ambience Healthcare
- Ambient AI
- Anduril
- Anyscale
- Applied Intuition
- Asserts.AI
- Azra Games
- Bayesian Health
- BigHat Biosciences
- BioAge
- Biodock
- Captions
- Captions
- Cartography Biosciences
- Character.AI
- Coactive AI
- Cresta
- Databricks
- Deepcell
- Descript
- Dialpad
- DoNotPay
- Drishti
- Dyno Therapeutics
- ElevenLabs
- Equals
- Firefly Health
- Flock Safety
- Freenome
- Genesis Therapeutics
- Gensyn
- Golden
- Hex
- Hippocratic AI
- Hippocratic AI
- Inductive Bio
- Instabase
- KoBold Metals
- Komodo Health
- Labelbox
- Levels Health
- Loom
- Macro
- Marker Learning
- Mem
- Memora Health
- Navan
- Omada Health
- OpenAI
- PLAI Labs
- Pahdo Labs
- People.ai
- Pinecone
- Pomelo Care
- Q Bio
- Rasa
- Ready Player Me
- Reface
- Regression Games
- Replicate
- Replit
- Rewind
- Rezo Therapeutics
- Ribbon Health
- Sardine
- Season Health
- Shield AI
- Skydio
- Sourcegraph
- Sprinter Health
- Steamship
- Tecton
- Thatch Health
- Topography Health
- Turquoise Health
- Ultima Genomics
- Valar Labs
- Ventus Therapeutics
- Waymark
- Waymo
- Zuma
- Zus Health
- insitro
Any investments or portfolio companies mentioned, referred to, or described on this page are not representative of all investments in vehicles managed by a16z and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by a16z is available here: https://a16z.com/investments/. Excluded from this list are investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets. Past results of Andreessen Horowitz’s investments, pooled investment vehicles, or investment strategies are not necessarily indicative of future results.
Featured AI Content
Recent AI Content
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It’s Not a Computer, It’s a Companion!
Chatbots have been around for decades, but this time is different. Today’s bots are making inroads into our social lives.
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The Next Token of Progress: 4 Unlocks on the Generative AI Horizon
How 4 key AI innovations will evolve over the next 6–12 months, and how founders can integrate these new advances into their businesses.
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Five Predictions for the Future of Learning in the Age of AI
If leveraged well, AI has the potential to greatly enhance students’ abilities to think critically and expand their soft skills.
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“Adventure is out there!”: Opportunities in AI x Travel
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Art Isn’t Dead, It’s Just Machine-Generated
Why AI models will replace artists long before they’ll replace programmers Perhaps the most mind-bending implication we’re seeing fr...
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The Long-Tail Problem in AI, and How Autonomous Markets Can Solve It
In the past decade, our progress in Artificial Intelligence has been staggering. We’ve gone from barely detecting cats in YouTube videos to building cars that can drive themselves. And yet, as ...
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The Generative AI Revolution will Enable Anyone to Create Games
Generative AI will completely reshape UGC and expand the games market beyond what many thought was possible.
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The New Industrial Revolution: Bio x AI
This new era of industrialized bio--enabled by AI as well as an ongoing, foundational shift in biology from empirical science to more engineered approaches--will be the next industrial revolution in human history.
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Using Generative AI to Unlock Probabilistic Products
Those who complain about hallucinations miss the point. A dispersion of outputs (including hallucinations) will unlock a whole new category of product design: probabilistic products.
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Emerging Architectures for LLM Applications
A reference architecture for the LLM app stack. It shows the most common systems, tools, and design patterns used by AI startups and tech companies.
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a16z Slack Debate: Will Generative AI Supplant Therapists, Game Makers…Friends?
There’s much more to generative AI than heroic avatars and tongue-in-cheek art. The potential applications are widespread, from drug discovery and therapy to writing, game development, educa...
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Aligning Founder Superpowers with Product Cycles
At this early stage in generative AI, technologists and product pickers will likely have the biggest impact on which companies emerge as winners.
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5 Founders on the Future of Data
Highlights from the a16z Data and AI Forum, featuring founders building products across the spectrum of data and AI use cases.
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Why AI Will Save the World
There's a full-blown moral panic about AI right now. But the real risk is losing the race to global AI technological superiority.
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AI Canon
A curated list of resources we’ve relied on to get smarter about modern AI, including generative AI, LLMs, and transformer models.
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Generative AI: The Next Consumer Platform
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Embracing the Future: How Chatbots Can Become Great Companions
In a world of retweets, upvotes, and right swipes, studies show that many of us still feel lonely. Thanks to generative AI, we potentially have a new solution: companion chatbots.
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For B2B Generative AI Apps, Is Less More?
We’ve watched large language models (LLMs) become mainstream over the past few years and have studied the implementations in the context of B2B applications. Despite some enormous technological ...
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Big Ideas in Tech for 2023: An a16z Omnibus
From entertainment franchise games to the precision delivery of medicines, small modular reactors to loads of AI applications, here are 40+ builder-worthy pursuits for 2023.
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Financial Services Will Embrace Generative AI Faster Than You Think
The emergence of generative AI could yield the largest transformation the financial services market has seen in decades.
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Taming the Tail: Adventures in Improving AI Economics
AI has enormous potential to disrupt markets that have traditionally been out of reach for software. These markets – which have relied on humans to navigate natural language, images, and physical space – represent a huge op...
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Navigating the High Cost of AI Compute
The generative AI boom is compute-bound and, as a result, a predominant factor driving the industry is simply the cost of training and inference.
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The Generative AI Revolution in Games
To understand how radically gaming is about to be transformed by generative AI, look no further than this recent Twitter post
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Who Owns the Generative AI Platform?
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Emerging Architectures for Modern Data Infrastructure
This is an updated version of a post we originally published in 2020. You can read the original version here....
The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the current or enduring accuracy of the information or its appropriateness for a given situation. In addition, this content may include third-party advertisements; a16z has not reviewed such advertisements and does not endorse any advertising content contained therein.
This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. (An offering to invest in an a16z fund will be made only by the private placement memorandum, subscription agreement, and other relevant documentation of any such fund and should be read in their entirety.) Any investments or portfolio companies mentioned, referred to, or described are not representative of all investments in vehicles managed by a16z, and there can be no assurance that the investments will be profitable or that other investments made in the future will have similar characteristics or results. A list of investments made by funds managed by Andreessen Horowitz (excluding investments for which the issuer has not provided permission for a16z to disclose publicly as well as unannounced investments in publicly traded digital assets) is available at https://a16z.com/investments/.
Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see https://a16z.com/disclosures for additional important information.