U.S. Deputy Secretary of Defense Kathleen Hicks will discuss the Department of Defense’s renewed commitment to innovation and the department’s new Replicator initiative, which is accelerating how the DoD procures and delivers capabilities to the warfighter at speed and scale. Following her keynote remarks, Dep. Sec. Hicks will sit down for an interview with Wall Street Journal national security and foreign policy editor Sharon Weinberger.

Technology companies have rediscovered their roots as innovators in national security and as critical partners to the Department of Defense. In this session, moderated by CNBC anchor Morgan Brennan, Anduril Cofounder and CEO Brian Schimpf lays out the case for how and why technology plays a critical role in helping ensure a safer world.

In this talk with a16z General Partner Ben Horowitz, Coinbase President and Chief Operating Officer Emilie Choi will discuss crypto’s potential to power the next-generation internet and bolster individual freedoms — two major reasons why America should not only embrace crypto, but take charge in shaping its future.

From judging inventions on “Shark Tank” to reshaping the image of NBA ownership, Mark Cuban is known for many things. In this chat with a16z General Partner David Ulevitch, he’ll discuss the importance of entrepreneurship for maintaining America’s status as the most innovative place on the planet. This includes making big bets, like he’s doing with his latest venture that seeks to upend the prescription drug markets.

Devoted Health founders Ed and Todd Park (who also served as U.S. CTO under President Obama) understand the connection between healthcare technology and patient outcomes as well as anybody. In this session with a16z General Partner Vijay Pande, they will discuss how a renewed focus on technology and compassion can deliver a new, better model for U.S. healthcare.

California has long been ground zero for the new: for new technologies, new frontiers, new arts and culture. In this session, moderated by a16z General Partner Katherine Boyle, California Forever CEO Jan Sramek discusses building an ambitious new city between San Francisco and Sacramento, why he firmly believes California’s best days are still ahead, and what he and his team are doing to realize that vision.

FBI Director Christopher Wray has had a front-row seat to the internet boom and how today’s technologies have reshaped crime, law enforcement, and prosecution. In this session, Director Wray chats with a16z General Partner David Ulevitch about keeping Americans safe and strengthening the public-private partnership in an age of AI, innovation espionage, and major technological advances across any number of fronts.

Representatives Mike Gallagher (R-WI) and Jake Auchincloss (D-MA) discuss why the United States must strengthen its technological advantage in areas like AI, develop next-generation manufacturing capabilities domestically, and rethink how Silicon Valley does business with China. Gallagher is Chair of the House Select Committee on the CCP, on which Auchincloss also serves.

In this presentation, a16z General Partner Martin Casado lays out the case for AI as a driving force behind incredible advancements in technology, creativity, and the human experience — not to mention efficiency improvements on par with, if not greater than, those delivered by the internet and the microchip.

Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and why we need to support AI research at all levels — from the classroom to the war room.

Senator Bill Cassidy (R-LA) and a16z General Partner Vijay Pande sit down with a16z’s Will Shrank to explore the shifting healthcare landscape, including the integration of AI and technology with biotech and healthcare, and how FDA reform could help more people get the treatments they need. Sen. Cassidy is the Ranking Member of the Senate Committee on Health, Education, Labor, and Pensions (HELP).

In this fireside chat, a16z Cofounder and General Partner Marc Andreessen sits down with economist, podcaster, and polymath Tyler Cowen to discuss the state of innovation in America, from recent AI advances to growing support for nuclear power. They’ll explain why the future many people claim to want — a better economy, better quality of life, and a safer world — is only possible if America leads.