It feels like software is shrinking while everyone is scrambling to buy generative AI. What’s changed, and how can you get a leg up?

Blackstone's CTO describes the qualities he looks for in early stage companies and predicts AI's impact on real estate, credit, and energy.

Scale AI founder and CEO Alexandr Wang discusses the three pillars of AI—models, compute, and data—and how abundant data is core to the evolution of gen AI.

Nikita Singareddy, cofounder and CEO of Fortuna Health, joins Will Shrank, MD, a16z Bio + Health venture partner. This is the second episode in our Medicaid Matters series.

Anime is just getting started - today, new technologies and business models are accelerating a once niche industry to even greater heights.

In this post, we look at how AI is increasing VSaaS revenue per customer by enabling vertical SaaS companies to take on tasks previously too complex for software.

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying the groundwork for innovations that are transforming industries today...

Over the next three episodes, we’re going to talk about why Medicaid matters, and the potential for technology to make it easier for enrollees to access and utilize the program. Our first guest is Mark Smith, MD, Clinical Professor of Medicine at UCSF.

Ambience cofounder Nikhil Buduma discusses how to build vertical applications with AI models, including in health care, and why tech expertise isn't enough.

This week in consumer tech: Apple’s big reveals, OpenAI’s multi-step reasoning, and Adobe Firefly’s video model.

Every white-collar role will have an AI copilot. Some of these roles will be fully automated with AI agents. 

When does virtual reality cease being virtual… and start to become reality? This episode digs deep into game design, philosophy, and mechanics with the maker of one of the world’s most iconic massive multiplayer online role playing games: EVE Online.

Vijay Pande, PhD, founding partner of a16z Bio + Health, joins Derrick Harris, host of the AI + a16z podcast.

Across the industries and companies that comprise American Dynamism, a decoupling of hardware and software for autonomy use cases is underway.

Discord Activities represents a significant opportunity for developers to create the next generation of web-based games.

Casey Means, MD, a Stanford-trained physician, cofounder of Levels, and author of the new book Good Energy, joins Vijay Pande, PhD, founding partner of a16z Bio + Health.

MotherDuck CEO Jordan Tigani discusses DuckDB's spiking popularity as the era of big data wanes, as well as the nexus of SQL and LLMs.

This month, the a16z fintech team went to Fintech DevCon, payments platform Moov’s annual conference for the fintech developer community.

As interest rates remain high, many SaaS businesses are reevaluating how much they give away in their free tier. Here's how to optimize.

Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare—twice that of any other developed nation—our outcomes still lag behind. In t...

Generative AI is enabling a foundational shift in creative storytelling, empowering a new class of human creators to tell stories not feasible before.

Consumers are effectively a new class of payor. And a number of opportunities exist to build solutions for those consumers (aka these new “micro payors”) to fund, navigate, and manage their healthcare purchases.

Greg Meyers, EVP and Chief Digital and Technology Officer at Bristol Myers Squibb, or BMS, joins Jorge Conde, general partner at a16z. This is a follow-up to their 2023 episode, where they discussed how biopharma can adapt to AI.

An acceleration of talent, capital, and research progress in the robotics domain could enable the development of a horizontal robotics platform.

Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market.

Today, thanks to AI, we are witnessing potentially the greatest transmutation in history. Software becomes labor. It’s the new E=MC2.

A16Z GAMES SPEEDRUN is coming back to SF! SR004 will run for 12 weeks starting January 6th, 2025, and culminate in a Demo Day during GDC week. Applications will be open from August 26th to September 30th, 2024.

We crunched the data to find out: Which gen AI apps are people actually using? And which are they returning to, versus dabbling and dropping?

A conversation about the role startups are playing in partnership with big banks and where Tim disagrees with the zeitgeist on the adoption of AI in financial services.

Michael Crackower, PhD, Chief Scientific Officer of Ventus Therapeutics, and Jason Burch, PhD, join Vineeta Agarwala, PhD, general partner at a16z Bio + Health.

Time-tested guidelines for starting a social presence from scratch. Plus, tools founders can use to know how, when, and what to post.

In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discuss are security experts Joel de la Garza and Naftali Harris. Incredibly...

Black Forest Labs founders Robin Rombach, Andreas Blattmann, and Patrick Esser discuss their new company building state-of-the-art image and video models.

Whereas we historically have viewed the low adoption of software as a liability, we now view that as an asset—we don't face the same sunk cost bias that might be slowing other industries down from taking full advantage of the latest AI innovations.

Logistics wins wars, and military logistics today means moving fuel. Advanced nuclear microreactors can replace fuel supply chains with on-site power, revolutionizing warfare and saving lives.

Bowen Liu, PhD, investing partner, and Surya Ganguli, PhD, venture partner, join Vijay Pande, PhD, general partner of a16z Bio + Health.

Once criticized for lacking ambition, French founders are now aiming to create the world’s largest companies. With a thriving ecosystem attracting talent from across Europe and the US, France is becoming a major player o...

Vijay Pande walks us through two decades of applying software engineering and AI to biotech and health care — from Folding@Home through AlphaFold and more.

Learn which parts of the stack to build or buy, and how to improve out-of-the-box models by helping customers select and ingest the right data.

Bruce Levine, PhD, the Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania, joins Jorge Conde, general partner, and Ginger Liau, partner at a16z Bio + Health.

Waymo co-CEO Dmitri Dolgov discusses how Waymo is using genAI to help them build safer, sustainable, and more accessible transportation.

The Olympics features over 11,000 athletes competing in 32 sports, attracting an audience of more than 10 million.

Blockchains are a way to build new networks, ensuring people have voice and choice in the networks they contribute to and use every day.

PromptFoo creator Ian Webster discusses the importance of red-teaming for AI safety and security, and of bringing those capabilities to more organizations.

With LLMs and AI-enabled data infrastructure, common sales activities will be redefined and completely new seller workflows will emerge.

On June 27th, the a16z team headed to New York City for the first-ever AI Artist Retreat at their office. This event brought together the builders behind some of the most popular AI creative tools, along with 16 artists,...

Martin Casado and Ion Stoica argue that open-source models will power innovation without compromising security.

Artists are at the forefront of the AI platform shift. As new high fidelity tools emerge along the creative stack, technology is extending the impact of filmmakers, designers, animators, illustrators, photographers, and multimedia artists.

This special episode is all about regional innovation — why are some places hubs of innovation, while others aren't?

In this episode, a follow-up to our episode Grand Challenges in Healthcare AI, Julie Yoo and Vijay Pande, a16z general partners, answer audience questions about AI applications in healthcare.

Command Zero CTO Dean de Beer discusses how large language models can help with cybersecurity incident response, and how to build products on LLMs.

In this talk, Juan Benet discusses his path to becoming one of the most prominent founders in web3, and his vision for Protocol Labs.

In this talk, Hilmar Pétursson discusses why CCP Games is embracing crypto, shares his thoughts about different gaming economies and more.

Gaming is not just entertainment—it's a revolution reshaping our culture, technology, and economy.

a16z General Partner David George interviews Capital Group's Mark Casey on his investment philosophy and what sends him into what he calls "barnacle mode."

John Crowley, President and CEO of Biotechnology Innovation Organization (BIO), joins Jorge Conde, general partner at a16z Bio + Health.

We discuss our favorite books and reading recommendations from team a16z crypto for summer 2024 on the web3 with a16z podcast.

Anyscale's Robert Nishihara discusses the challenges of training and running AI models at scale, and how a focus on video data will change generative AI.

The Talent x Opportunity Fall 2024 cohort is a group of talented founders building companies that range from making it easy to find the style that best expresses who you are to providing real-world rewards through gaming.

Lawrence Ingrassia, author and journalist, joins Vineeta Agarwala, general partner, and Kris Tatiossian, editorial lead at a16z Bio + Health.

Less than two years since the breakthrough of text-based AI, we now see incredible developments in multimodal AI models and their impact on millions of users.

Tim Roughgarden, Scott Kominers, and Pranav Garimidi discuss incentives, market design and mechanism design within the infrastructure and application layers.

Jonathan Swerdlin, cofounder and CEO, and Mark Hyman, MD, cofounder and Chief Medical Officer of Function Health join Vijay Pande, general partner, and Daisy Wolf, investment partner of a16z Bio + Health.

a16z crypto research partners explore diverse aspects of cryptography, delving deeply into their respective research areas.

In this special episode, Marc and Ben dive deep into the REAL story behind the creation of Netscape—a web browser co-created by Marc that revolutionized the internet and changed the world. As Ben notes at the top, until...

The time has come to stand up for Little Tech. Bad government policies are now the #1 threat to Little Tech. We believe American technology supremacy, and the critical role that Little Tech startups play in ensuring that supremacy, is a first class political issue on par with any other.

Jiaming Song and Anjney Midha discuss Luma's Dream Machine 3D model that shows abilities to reason about the world across a variety of aspects.

Here's where AI agents and software can have the most immediate impact on your business, and make you more efficient and productive.

Pros and cons of existing NFT royalty designs, plus two new approaches to royalties that leverage incentive mechanisms.

Is it time to hand over cybersecurity to machines amidst the exponential rise in cyber threats and breaches?

Jonathan Bush, founder and CEO of Zus Health, and Chris Severn, cofounder and CEO of Turquoise Health, join Julie Yoo, general partner, and Colin Rom, head of public policy for a16z Bio + Health.

Generative AI is working its way into everything, and firms want to show they are implementing this new tech — especially those that serve the accounting market.

BNY's Akash Shah on the company's approach to adopting AI and what advice he would give to fintech startup founders.

Maggie Hsu and Pyrs Carvolth discuss the intricacies of GTM strategies, explore various models and motions, and walk through a comprehensive checklist.

Alasdair Monk discusses how generative AI is changing how developers — and the those building for developers — interact with the tools of their trade.

a16z General Partner Angela Strange, Plaid CEO Zach Perret, and Marqeta CEO Simon Khalaf discuss how AI and fintech will shape the future of banking.

Senate Bill 1047 is designed to apply to models trained above certain compute and cost thresholds. It also holds developers legally liable for the downstream use or modification of their models.