Managing enterprise networks with thousands of users and endpoints has been hard enough. Now that large enterprise networks routinely include hundreds of thousands of nodes it’s amazingly difficult and time-consuming (we’re talking days often) to get definitive answers to seemingly simple questions like, how many PCs do I have running? Never mind, how many PCs do I have that could be at risk of the Heartbleed virus? Tanium, the most recent company to join the a16z portfolio, offers a systems management and security tool that allows administrators to ask virtually any question about the configuration, performance, and complexion of an enterprise network and get an answer in seconds. Tanium CTO and Co-founder Orion Hindawi and a16z Board Partner Steven Sinofsky discuss the origins of Tanium; the invention of the “linear peer-to-peer communications” architecture that turbo-charges the Tanium solution; and with Internet of Things coming online fast, the prospect of networks quickly going to millions and billions of nodes.