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Digital Health Builders

Conversations with bold entrepreneurs and builders who are reimagining healthcare and life sciences

The New Paths to Market in Digital Health

We are seeing a revolution in how digital health companies distribute their product. Some are finding bottom up traction with end consumers as a path to enterprise buyer. Others are pioneering risk-based contracting, developing multi-sided marketplaces, or taking advantage of new aggregator partnerships. a16z general partner Julie Yoo explains why the go-to-market (GTM) for digital health startups is shifting and the six new GTM motions that she sees emerging.

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Latest in Digital Health

  • Behind the Buy: Payors and Providers on AI Adoption
    Julie Yoo, Jay Rughani, Kris Tatiossian, and Olivia Webb

    This episode features interviews with payor and provider leaders about what they’re seeing and how they’re thinking about AI. Guided by Julie Yoo, general partner, and Jay Rughani, investment partner at a16z Bio + Health, you'll hear from the executives about how they're utilizing AI, the KPIs they use to gauge effectiveness, and what they consider to be a good partnership.

  • The Most Interesting Healthcare Companies You’ve Never Heard Of with Julie Klapstein
    Julie Klapstein, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

  • Finding PMF in Healthcare (After Tasting it Elsewhere) with Eren Bali and Max Cohen
    Eren Bali, Max Cohen, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Max Cohen, cofounder and CEO of Sprinter Health, and Eren Bali, founder and CEO of Carbon Health, join Julie Yoo, general partner at a16z Bio + Health.

  • How to Build an AI-Native Health Plan with Mario Schlosser
    Mario Schlosser, Julie Yoo, Kris Tatiossian, and Olivia Webb

    Mario Schlosser, cofounder, former CEO, and current President of Technology at Oscar Health, joins Julie Yoo of Bio + Health. The conversation explores how AI advancements can revolutionize traditional healthcare models by enhancing efficiency, personalizing care journeys, and integrating real-time data insights.

  • While the Google --> WebMD --> Friend protocol may be a common way to enter into the healthcare system, it is certainly not an optimal one. Most of us are not well-equipped to self-diagnose from a list of possible conditions, and our friends who work in healthcare often don’t have the exact expertise we need.

  • CMO vs. CPO with Peter Shalek and Reena Pande
    Justin Larkin, Reena Pande, Peter Shalek, Julie Yoo, Kris Tatiossian, and Olivia Webb

    As Julie mentions during the episode, there’s international relations, and then there’s CMO/CPO relations. Peter and Reena talk about working together to improve their relationship and the outcomes of their teams, and they get granular about what worked and what didn’t.

  • At the end of the day, even the best AI models will fail if they don’t figure out a way to achieve broad distribution and profitable monetization, so it’s important to understand the psyche of the buyers and decision makers who will determine the fate of your products.

  • Commercializing AI in Healthcare: The Jobs to be Done
    Jay Rughani, Daisy Wolf, Vijay Pande, and Julie Yoo

    Building specialist AIs to perform healthcare tasks offers the most challenging technical problems in the field today, as well as the greatest opportunity for impact.

  • The Path of a Healthtech CTO with Margaret McKenna
    Margaret McKenna, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Margaret McKenna, former CTO of Devoted Health and our newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

  • Putting the Pro in Provider Networks with Dan Rosenthal
    Dan Rosenthal, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Dan Rosenthal, a provider network expert and the newest advisory partner for a16z Bio + Health, joins Julie Yoo, general partner.Together, they talk about the 101 and 201 of provider networks, tactical advice for digital health builders, and how AI could theoretically change the way networks are constructed.

  • The most impactful companies are built at the frontier, and healthcare is the next frontier. It’s time to put our tech skills to work. The mother of all markets is ripe for disruption.

  • Healthtech x Fintech’s Biggest Prize: The Financial Operating System for Healthcare
    Marc Andrusko, Annie Collins, David Haber, Daisy Wolf, and Julie Yoo

    Consider this: most healthcare providers are flying blind when it comes to their finances.

  • Risk-based Contracting for Value-based Care
    Justin Larkin and Julie Yoo

    COVID has strained our healthcare system, payors are feeling the squeeze of rising costs, and patients are bearing the brunt of the current system’s shortcomings. As a result, healthcare is undergoing a transformat...

  • B2C2B in Digital Health
    Jay Rughani and Julie Yoo

    B2C2B — also known as bottom up — has helped companies like Slack, Zoom, Dropbox, and other software companies break into B2B. Now B2C2B is coming to digital health, as a wave of startups are first selling products a...

  • Digital health is currently one of the fastest growing VC-funded segments, and it’s time to update the GTM playbooks for the current (and future) market.

  • Today’s episode is all about the history and future of infusing tech into healthcare with the goals of improving outcomes and lowering costs, and features one of the leading voices in this field, Jonathan Bush. Jonatha...

  • Bio Eats World: The Problem with Urgent Care
    Vineeta Agarwala, Justin Larkin, and Lauren Richardson

    When it comes to healthcare, the topic of how expensive it is and what we can do to lower costs is always top of mind. One area with particularly steep costs is the emergency department. These are hospital departments th...

  • Bio Eats World: Value Versus Volume (in Healthcare)
    Todd Park, Vijay Pande, and Hanne Winarsky

    The way we pay for healthcare in the US has long been by fee-for-service: per doctor visit, per test, per surgery, per hospital stay. But that system has led to rapidly escalating volumes of services and cost to the syst...

  • Bio Eats World: May I Have Your Insurance Card Again, Please?
    Bill Frist, Malinka Walaliyadde, Julie Yoo, and Hanne Winarsky

    There’s been a lot of talk (including on this show!) about the many kinds of innovations and technologies changing healthcare delivery for clinicians and patients. But what’s happening behind the scenes in he...

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

  • Behind the Buy: Payors and Providers on AI Adoption
    Julie Yoo, Jay Rughani, Kris Tatiossian, and Olivia Webb

    This episode features interviews with payor and provider leaders about what they’re seeing and how they’re thinking about AI. Guided by Julie Yoo, general partner, and Jay Rughani, investment partner at a16z Bio + Health, you'll hear from the executives about how they're utilizing AI, the KPIs they use to gauge effectiveness, and what they consider to be a good partnership.

  • The Most Interesting Healthcare Companies You’ve Never Heard Of with Julie Klapstein
    Julie Klapstein, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

  • Finding PMF in Healthcare (After Tasting it Elsewhere) with Eren Bali and Max Cohen
    Eren Bali, Max Cohen, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Max Cohen, cofounder and CEO of Sprinter Health, and Eren Bali, founder and CEO of Carbon Health, join Julie Yoo, general partner at a16z Bio + Health.

  • How to Build an AI-Native Health Plan with Mario Schlosser
    Mario Schlosser, Julie Yoo, Kris Tatiossian, and Olivia Webb

    Mario Schlosser, cofounder, former CEO, and current President of Technology at Oscar Health, joins Julie Yoo of Bio + Health. The conversation explores how AI advancements can revolutionize traditional healthcare models by enhancing efficiency, personalizing care journeys, and integrating real-time data insights.

  • CMO vs. CPO with Peter Shalek and Reena Pande
    Justin Larkin, Reena Pande, Peter Shalek, Julie Yoo, Kris Tatiossian, and Olivia Webb

    As Julie mentions during the episode, there’s international relations, and then there’s CMO/CPO relations. Peter and Reena talk about working together to improve their relationship and the outcomes of their teams, and they get granular about what worked and what didn’t.

  • The Path of a Healthtech CTO with Margaret McKenna
    Margaret McKenna, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Margaret McKenna, former CTO of Devoted Health and our newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

  • Putting the Pro in Provider Networks with Dan Rosenthal
    Dan Rosenthal, Kris Tatiossian, Olivia Webb, and Julie Yoo

    Dan Rosenthal, a provider network expert and the newest advisory partner for a16z Bio + Health, joins Julie Yoo, general partner.Together, they talk about the 101 and 201 of provider networks, tactical advice for digital health builders, and how AI could theoretically change the way networks are constructed.

  • Today’s episode is all about the history and future of infusing tech into healthcare with the goals of improving outcomes and lowering costs, and features one of the leading voices in this field, Jonathan Bush. Jonatha...

  • Bio Eats World: The Problem with Urgent Care
    Vineeta Agarwala, Justin Larkin, and Lauren Richardson

    When it comes to healthcare, the topic of how expensive it is and what we can do to lower costs is always top of mind. One area with particularly steep costs is the emergency department. These are hospital departments th...

  • Bio Eats World: Value Versus Volume (in Healthcare)
    Todd Park, Vijay Pande, and Hanne Winarsky

    The way we pay for healthcare in the US has long been by fee-for-service: per doctor visit, per test, per surgery, per hospital stay. But that system has led to rapidly escalating volumes of services and cost to the syst...

  • Bio Eats World: May I Have Your Insurance Card Again, Please?
    Bill Frist, Malinka Walaliyadde, Julie Yoo, and Hanne Winarsky

    There’s been a lot of talk (including on this show!) about the many kinds of innovations and technologies changing healthcare delivery for clinicians and patients. But what’s happening behind the scenes in he...

  • While the Google --> WebMD --> Friend protocol may be a common way to enter into the healthcare system, it is certainly not an optimal one. Most of us are not well-equipped to self-diagnose from a list of possible conditions, and our friends who work in healthcare often don’t have the exact expertise we need.

  • At the end of the day, even the best AI models will fail if they don’t figure out a way to achieve broad distribution and profitable monetization, so it’s important to understand the psyche of the buyers and decision makers who will determine the fate of your products.

  • Commercializing AI in Healthcare: The Jobs to be Done
    Jay Rughani, Daisy Wolf, Vijay Pande, and Julie Yoo

    Building specialist AIs to perform healthcare tasks offers the most challenging technical problems in the field today, as well as the greatest opportunity for impact.

  • The most impactful companies are built at the frontier, and healthcare is the next frontier. It’s time to put our tech skills to work. The mother of all markets is ripe for disruption.

  • Healthtech x Fintech’s Biggest Prize: The Financial Operating System for Healthcare
    Marc Andrusko, Annie Collins, David Haber, Daisy Wolf, and Julie Yoo

    Consider this: most healthcare providers are flying blind when it comes to their finances.

  • Risk-based Contracting for Value-based Care
    Justin Larkin and Julie Yoo

    COVID has strained our healthcare system, payors are feeling the squeeze of rising costs, and patients are bearing the brunt of the current system’s shortcomings. As a result, healthcare is undergoing a transformat...

  • B2C2B in Digital Health
    Jay Rughani and Julie Yoo

    B2C2B — also known as bottom up — has helped companies like Slack, Zoom, Dropbox, and other software companies break into B2B. Now B2C2B is coming to digital health, as a wave of startups are first selling products a...

  • Digital health is currently one of the fastest growing VC-funded segments, and it’s time to update the GTM playbooks for the current (and future) market.

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

  • It’s Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

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