Building in Healthcare

Julie Klapstein, founding CEO of Availity, long-time healthcare executive, and a16z Bio + Health's newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health.

Max Cohen, cofounder and CEO of Sprinter Health, and Eren Bali, founder and CEO of Carbon Health, join Julie Yoo, general partner at a16z Bio + Health.

Vijay Pande, founding partner of Bio + Health, is joined by Daphne Koller, Andrew Ng, Aviv Regev, and Jakob Uszkoreit. Vijay leads us on a reflective journey through the monumental achievements in AI from the 1980s to today, with a focus on the progress in healthcare and life sciences.

All this to say—it’s time to figure out how to access, pay for, and deliver curative therapies (amongst other high-cost, complex, specialty drugs), at scale. Let’s dive into the specific challenges that need to be surmounted to get this right.

Bio Eats World is now Raising Health! On this first episode of Raising Health, Sean Duffy, cofounder and CEO of Omada Health, joins Vijay Pande, founding partner of Bio + Health.

100% of stock trades used to be made by humans. Today, 80% are made by computer algorithms. AI is about to bring a similar revolution to healthcare. Over the next few decades, at least half of the $4.3 trillion dollar American healthcare industry will be AI-driven.

Mario Schlosser, cofounder, former CEO, and current President of Technology at Oscar Health, joins Julie Yoo of Bio + Health. The conversation explores how AI advancements can revolutionize traditional healthcare models by enhancing efficiency, personalizing care journeys, and integrating real-time data insights.

While the Google --> WebMD --> Friend protocol may be a common way to enter into the healthcare system, it is certainly not an optimal one. Most of us are not well-equipped to self-diagnose from a list of possible conditions, and our friends who work in healthcare often don’t have the exact expertise we need.

As Julie mentions during the episode, there’s international relations, and then there’s CMO/CPO relations. Peter and Reena talk about working together to improve their relationship and the outcomes of their teams, and they get granular about what worked and what didn’t.

Building specialist AIs to perform healthcare tasks offers the most challenging technical problems in the field today, as well as the greatest opportunity for impact.

Margaret McKenna, former CTO of Devoted Health and our newest advisory partner, joins Julie Yoo, general partner at a16z Bio + Health.

Dan Rosenthal, a provider network expert and the newest advisory partner for a16z Bio + Health, joins Julie Yoo, general partner.Together, they talk about the 101 and 201 of provider networks, tactical advice for digital health builders, and how AI could theoretically change the way networks are constructed.

Jeffrey Kaditz, repeat founder and current founder, CEO, and CTO of Q Bio, joins Vijay Pande, founding partner of a16z Bio + Health.

Today’s episode is with Mark Cuban, founder of multiple businesses, owner of the Dallas Mavericks, one of the sharks on Shark Tank, and cofounder of the Mark Cuban Cost Plus Drug Company.

Today’s episode is with Sean Duffy, cofounder and CEO of Omada Health. He is joined by a16z Bio + Health general partner Julie Yoo and investment partner Jay Rughani.

Today’s episode is with Florian Otto, cofounder and CEO of Cedar. He is joined by a16z Bio + Health general partner Julie Yoo.

In this episode, a16z Bio + Health general partner Julie Yoo chats with Bassett Healthcare Network president and CEO Tommy Ibrahim.

Today’s episode is with Sam Corcos, CEO and cofounder of Levels Health. Sam is joined by Vijay Pande, general partner at a16z Bio + Health.

Bio + Health deal partner Daisy Wolf joins Sarah Thomas, general counsel at Sameday Health, for a fireside chat on the topic of regulation in telehealth—during Covid and on.

The most significant bottleneck in the adoption of healthcare technology to date has been distribution. Over the last decade, generations of digital health companies have struggled to reach escape velocity—not because th...

COVID has strained our healthcare system, payors are feeling the squeeze of rising costs, and patients are bearing the brunt of the current system's shortcomings. As a result, healthcare is undergoing a transformation, f...

Network effects can be found powering almost every major technology company, from messaging apps and workplace collaboration tools, like Slack and Zoom, to marketplaces, like Airbnb and Instacart to even the internet itself. In this podcast, we look at the role of network effects creator-driven social platforms, with Alexis Ohanian, cofounder from Reddit, Paul Davison, cofounder from Clubhouse, and a16z general partner Andrew Chen, whose new book, "The Cold Start Problem: How to Start and Scale Network Effects" comes out this week (see coldstart.com for more). We cover: how do you cold start and get your first creators? How does your relationship to creators change as you scale? And how is web3 changing the incentives and dynamics around network effects?

B2C2B — also known as bottom up — has helped companies like Slack, Zoom, Dropbox, and other software companies break into B2B. Now B2C2B is coming to digital health, as a wave of startups are first selling products and s...

Digital health is currently one of the fastest growing VC-funded segments, and it’s time to update the GTM playbooks for the current (and future) market.

It's Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

It's Time to Heal is a special package about engineering the future of bio and healthcare. See more at: https://a16z.com/time-to-heal/.

Looking for a job in the 2020s will be very different from looking for a job in the 2000s, or even the 2010s. In this new era of reduced budgets, open-ended hiring freezes, and a shape-shifting workforce of career change...

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It used to be that when you got sick, your doctor would come to you. But as medical equipment, expertise and knowledge, and the entire modern healthcare system evolved, we created grand institutions to make granting heal...

Primary care was meant to be the front door to the healthcare system: the one-stop-shop we rely on for all of our general healthcare needs, and to help us navigate the rest of the convoluted care delivery ecosystem.

Every Western institution was unprepared for the coronavirus pandemic, despite many prior warnings. This monumental failure of institutional effectiveness will reverberate for the rest of the decade, but it's not too ear...

Julie Yoo is a General Partner at Andreessen Horowitz where she leads investments in healthcare technology, with a focus on companies that are modernizing how we access, pay for, and experience the healthcare system.

The federal agency known as the FDA, or the Food and Drug Administration, was born over a 100 years ago—at the turn of the industrial revolution, in a time of enormous upheaval and change, and rapidly emerging technology...

The landscape of cell and gene therapies—where cells or genes are engineered to treat disease—is changing rapidly, with 4 US approvals since 2017 and 40-60 launches projected by 2030. Entrepreneurs, biopharma leaders, an...

We believe right now is a truly transformative moment in the healthcare market—particularly in care delivery. In this article, I’ll describe some of the tailwinds that are creating this unique opportunity in health care...

The challenges we face in American healthcare are so well known they almost require no introduction. Costs of American healthcare -- now at nearly 18% of GDP, with estimates showing ~$3.5T spend on healthcare in 2017 alo...

The U.S. spends over $3 trillion annually and healthcare accounts approaches 20% of our GDP -- this is clearly an industry that is ripe with opportunity and lots of activity. But it is also rife with waste, operational i...

watch time: 8 minutes

watch time: 6 minutes

AI teaching computers to make business sense of ill-lit 3D objects. We invested in Doxel, because of Saurabh Ladha, and his co-founder Robin Singh. They are without much parallel when it comes to the tech of 3D semantic...

It’s a common nightmare for programmers to come in late to a project or organization and then have to make sense of a complex “spaghetti mess” of code created over the previous 10 years -- a technical debt that takes hug...

watch time: 22 minutes

With all the activity and conversation around healthcare reform, I thought it would be useful to share this short, internal deck from one of our portfolio companies, Cardiogram, via their CEO Brandon Ballinger. It quickl...

"Now let me holler at ya partner, spit this game

We only have about a million physicians in the United States -- but they’re about to get reinforcements.

1/Late night tweetstorm addendum to earlier series on unbundling (https://t.co/ecgBveoiMj) and rebundling (https://t.co/0fw9alDKh3)...

1/"The VA scheduling system scheduled its first appointment in April of 1985. It has not changed in any appreciable manner since that date."

1/For the following, substitute rapidly rising tide of products & services for "Coke":

One of the oft-repeated stories my father used to tell me was the time he met Johnny Weissmuller. Weissmuller was the Michael Phelps or Mark Spitz of his generation, garnering five Olympic gold medals, 52 U.S. championsh...

There is a recurring theme that the tech industry is busy cranking out fluffy social apps rather than hardcore technology. Not the case, say Chris Dixon, Benedict Evans and Balaji Srinivasan. Not only are tech entreprene...

 

Bernard Tyson, Chairman and CEO of Kaiser Permanente, speaks plainly when it comes to where technology fits into his $50 billion healthcare business. "For me, it is the centerpiece," Tyson says. "The most important inves...

SpiderNet has been planning to release version 1.0 of its product in Q2 of this year. However, after the new VP of Engineering looks into the schedule and deliverables, he informs you that the product will be delayed, po...

[This blog post was originally published on All Things Digital on March 17, 2010.]