Therapeutics

We’re rebooting our Journal Club series! Going forward, these episodes will be interspersed in our regular feed. In this episode, Ben Cravatt, Professor in the Department of Chemistry at the Scripps Research Instit...

Kevin Parker, cofounder and CEO of Cartography Biosciences, joins Jorge Conde, general partner at a16z Bio + Health, and Olivia Webb, editorial lead.

The FDA just approved the first ever videogame that can now be legally marketed and prescribed as a medicine. It’s a game called EndeavorRX (formerly known as Project EVO and developed by Akili Interactive based on...

a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature — what papers we’re reading, and why they matter from our perspective at the intersection of biology...

The RNA technology underlying both the Moderna and Pfizer/BioNTech vaccines could give us our fastest ticket out of the COVID-19 pandemic. With their rapid development and the early signs of success, RNA-based therapeuti...

The entire healthcare system is built around the idea that we can detect, diagnose, and manage disease effectively for patients. This pandemic has been a stress test of that capability, and we have roundly failed that te...

There’s been a lot of talk lately about possibilities for treating aging—from blood transfusions from old mice to young, to eradicating “zombie” cells, to taking daily rapamycin and metformin pills to extend your...

1/ RCTs vs RWE’s has become a heated debate. Some believe that RWE would be cheaper and better, as there’s more data. Others believe that RCTs are the only statistically validated means to test a drug. Who’s right?

Editor’s note: This is a list of selected resources on the novel coronavirus (formerly known as as 2019 n-CoV, now known as SARS-CoV-2) that causes COVID-19 disease. The list spans everything from official sources,...

We are at the beginning of a new era for how we treat one of humankind’s oldest and worst foes—cancer. In this talk, given at the annual a16z Summit, Jonathan Lim, CEO and cofounder of Erasca, shows us where we are i...

Genetic engineering is in some sense as old as human history, when we first began selectively breeding livestock and crops. Then came the advent of biotech, and our ability to read, copy, edit, and now write DNA directly...

Novartis recently announced what is now the most expensive medicine in history: Zolgensma, a newly-approved gene therapy to treat a devastating disease called Somatic Muscular Atrophy, or SMA, will have a price tag of $2...

watch time: 16 minutes