Guido Appenzeller

Guido Appenzeller

Infra Investing Team

About

Guido Appenzeller is an investor at Andreessen Horowitz, where he focuses on AI, infrastructure, open source technology, and silicon.

He previously was the chief technology officer for Intel’s Data Platforms Group (DPG), where he was responsible for technical direction and pathfinding across the data platforms portfolio.

Prior to joining Intel, Guido was chief product officer at Yubico, where he focused on product development and strategy. Guido was previously the CTO, Cloud & Networking at VMware, where he helped define VMware’s multi-cloud strategy and was part of the team that grew NSX to a $1 billion product line. Before VMware, he co-founded Big Switch Networks (acquired by Arista) and Voltage Security (acquired by HP), leading those companies as CEO and CTO, respectively.

Guido received a Test of Time Award from SIGCOMM. He was named to the MIT TR35, with Voltage Security was named a Technology Pioneer by the World Economic Forum and one of the 100 Most Intriguing Entrepreneurs by Goldman Sachs.

From 2008 to 2010 Guido was a Consulting Assistant Professor at Stanford University. Guido holds a PhD from Stanford University and MS (Diplom) in Physics from the Karlsruhe Institute of Technology.

Latest Content by Guido

Growth

Investing in Nexthop AI

Raghu Raghuram, Shangda Xu, and Guido Appenzeller
Infra

Investing in QuiverAI

Yoko Li, Guido Appenzeller, and Martin Casado
Infra

Investing in Mirelo

Guido Appenzeller and Justine Moore
Infra

Investing in Unconventional

Matt Bornstein, Guido Appenzeller, and Raghu Raghuram
Infra

The Trillion Dollar AI Software Development Stack

Guido Appenzeller and Yoko Li
Infra

Investing in Relace

Yoko Li, Guido Appenzeller, and Martin Casado
American Dynamism

Dylan Patel on the AI Chip Race – NVIDIA, Intel & the US Government vs. China

Sarah Wang, Guido Appenzeller, Erik Torenberg, and Dylan Patel
Infra

Dylan Patel: GPT-5, NVIDIA, Intel, Meta, Apple

Dylan Patel, Erin Price-Wright, Guido Appenzeller, and Erik Torenberg
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